cytotoxic drug

同根派生

Pathological change is chronic and continual advancement,patients can emerge renal inadequacy,uraemia.excitatory autacoid and cytotoxic drug have bad curative effect and major adverse reaction.
病变呈慢性的进行性发展，可逐渐出现肾功能不全、尿毒症。激素、细胞毒类药物疗效欠佳，且有较大的不良反应。
Adriamycin is frequently used in combination chemotherapy regiments with other cytotoxic drugs.
阿霉素常与其他细胞毒药物合用于化疗方案。
The mechanism by which chronic-phase CML cells become resistant to conventional cytotoxic drugs, such as hydroxyurea, is unknown.
慢性期CML细胞对常规细胞毒药物，如羟基脲产生抗药性的机理还不清楚。
Antibody-drug conjugates enhance the antitumor effects of antibodies and reduce adverse systemic effects of potent cytotoxic drugs.
抗体偶联药物能提高抗体的抗肿瘤能力并减少有效细胞毒性药物的系统性副作用。
The most effective cytotoxic drugs for treatment of metastatic breast cancer are capecitabine, doxorubicin, gemcitabine, the taxanes paclitaxel and docetaxel, and vinorelbine.
治疗转移性乳腺癌的最有效细胞毒类药有卡培他滨、阿霉素、二氟脱氧胞嘧啶、紫杉烷类（紫杉醇和紫杉萜[泰素帝]）、长春瑞滨等。